Soft Tissues Cancer

Cancerous solid soft tissue tumors, also known as soft tissue sarcomas, originate in the soft tissues of the body, such as muscles, fat, blood vessels, nerves, and connective tissues. These tumors can be malignant (cancerous) or benign. Malignant soft tissue tumors, while rare, can be aggressive and spread to other parts of the body.

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Symptoms

Soft tissue sarcoma symptoms vary by tumor size, location, and spread. Common signs include a slow-growing, painless lump under the skin that may become painful as it presses on nearby tissues. If near a joint, it may cause stiffness or limit movement. Tumors affecting internal organs can cause pain, bloating, digestive issues, or difficulty breathing. As the cancer progresses, general symptoms like weight loss, fatigue, and fever may occur, indicating advanced stages or spread.

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Risk Factors

The exact cause of soft tissue cancer is unknown, but several risk factors increase the likelihood. Age, particularly adults 40-60, is a significant factor. Genetic conditions like Li-Fraumeni syndrome, neurofibromatosis, and Gardner's syndrome also raise the risk. Radiation exposure, especially from childhood cancer treatment, is another factor. Chronic lymphedema increases the risk of angiosarcoma, and environmental factors, including chemical or toxin exposure, may contribute, though research is ongoing.

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Subtypes of

Soft Tissues Cancer

Liposarcoma

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Liposarcoma is a type of cancer that originates in the fat cells. It is the most common soft tissue sarcoma in adults, usually occurring in the abdomen or thighs.

Subtypes:

Well-Differentiated Liposarcoma
Dedifferentiated Liposarcoma
Myxoid Liposarcoma
Pleomorphic Liposarcoma

Leiomyosarcoma

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Leiomyosarcoma is a type of cancer that originates in smooth muscle tissue, commonly found in the abdomen, uterus, and blood vessels.

Subtypes:

Uterine Leiomyosarcoma
Retroperitoneal Leiomyosarcoma
Gastrointestinal Leiomyosarcoma
Cutaneous Leiomyosarcoma
Visceral Leiomyosarcoma
Vascular Leiomyosarcoma

Rhabdomyosarcoma

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Rhabdomyosarcoma is a malignant tumor that arises from skeletal muscle tissue, most commonly affecting children and adolescents. It can occur in any skeletal muscle but is most commonly found in the head, neck, urinary bladder, and limbs.

Subtypes:

Embryonal Rhabdomyosarcoma
Alveolar Rhabdomyosarcoma
Pleomorphic Rhabdomyosarcoma
Spindle Cell Rhabdomyosarcoma

Synovial Sarcoma

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Synovial sarcoma is a rare and aggressive form of soft tissue cancer that most commonly affects the limbs, particularly the knees and upper limbs. It typically occurs in young adults.

Subtypes:

Classical Synovial Sarcoma
Monophasic Synovial Sarcoma
Biphasic Synovial Sarcoma

Angiosarcoma

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Angiosarcoma is a rare and aggressive cancer that originates in the blood vessels or lymphatic vessels. It can occur in any part of the body but is most often found in the skin, breast, liver, and spleen.

Subtypes:

Cutaneous Angiosarcoma
Visceral Angiosarcoma
Breast Angiosarcoma
Hepatic Angiosarcoma
Post-Radiation Angiosarcoma

Malignant Peripheral Nerve Sheath Tumor (MPNST)

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MPNST is a cancer that starts in the cells that cover the peripheral nerves. It is most commonly associated with a genetic disorder called neurofibromatosis type 1 (NF1).

Subtypes:

Classical MPNST
Radiation-Induced MPNST

Fibrosarcoma

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Fibrosarcoma originates in fibrous tissues, such as tendons or ligaments. It is most common in adults but can occur at any age.

Subtypes:

Adult-type Fibrosarcoma
Juvenile Fibrosarcoma

Dermatofibrosarcoma Protuberans (DFSP)

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Dermatofibrosarcoma protuberans is a slow-growing cancer that develops in the deep layers of the skin and is often found on the trunk or limbs.

Subtypes:

Classic DFSP
Fibrosarcomatous DFSP

Kaposi Sarcoma

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Kaposi sarcoma is a cancer that involves the blood vessels and is most commonly associated with human herpesvirus 8 (HHV-8) infection. It can occur on the skin or in internal organs like the lungs and digestive tract.

Subtypes:

Classic Kaposi Sarcoma

Endemic Kaposi Sarcoma

Epidemic (AIDS-Related) Kaposi Sarcoma
Iatrogenic Kaposi Sarcoma

Gastrointestinal Stromal Tumor of the digestive tract (GIST)

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GISTs are cancers that arise in the digestive tract, most commonly in the stomach or small intestine. They develop from interstitial cells of Cajal, which are involved in the movement of the digestive tract.

Subtypes:

Spindle Cell GIST
Epitheloid GIST
Mixed GIST

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Disclaimer: This list provides a comprehensive overview of some of the most common cancerous solid tumors, including theirtypes, subtypes, symptoms and risk factors. However, it is important to note that this list may not capture everypossible tumor type and subtype within this category. Cancer research is continually evolving, and new types andsubtypes may emerge over time. For a complete and personalized understanding of a cancer type or sub-type,individuals should consult medical professionals or oncologists. This information is intended for educationalpurposes only and should not be used as a substitute for professional medical advice or diagnosis.